Jul 06, 2017 Others

Where would the director of the Blood Bank who is screening donated blood for HIV antibody want to put the cutoff? What would be the potential problem caused by this decision?

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Screening for Diseases: Test Sensitivity and Specificity

Instructions:

Please see attach file and answer the question 1. What would be the impact on this test`s sensitivity if you moved the cutoff for a positive result from A to B? What about specificity? What would happen to sensitivity and specificity if you moved the cutoff from A to C? Where would you put the cutoff for this test? What is the relationship between sensitivity and specificity for any given test? 2. Where would the director of the Blood Bank who is screening donated blood for HIV antibody want to put the cutoff? What would be the potential problem caused by this decision? Where would an investigator enrolling high-risk patients in a clinical trial for an experimental, potentially toxic antiretroviral draw the cutoff? What would be the potential problem caused by this decision? In your answer please detail possible ethical and legal issues of possible concern.

Content:

Screening for Diseases Name Course Instructor Date  1] What would be the impact on this test`s sensitivity if you moved the cutoff for a positive result from A to B? What about specificity? What would happen to sensitivity and specificity if you moved the cutoff from A to C? Where would you put the cutoff for this test? What is the relationship between sensitivity and specificity for any given test? The sensitivity of the screening test relates to

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